State Research Institute of Organic Chemistry and Technology (GosNIIOKhT)

State Research Institute of Organic Chemistry and Technology (GosNIIOKhT), Moscow

Genaral Director - Viktor A. Petrunin
Head of Department - Anton Y. Utkin (Presenter at conference)

GosNIIOKhT
Shosse Entuziastov, 23, Moscow
E-mail: Dr. Utkin
Tel: 7-095-273-8736
Fax: 7-095-273-2218

First Annual Chemical Science and Commercialization Conference
Presentation

Introduction (English) (Russian)
"Novel Immunomodulator with anti-tumor activity" (English) (Russian)
"Development of New Technology and Equipment for Production of BIODIESEL (Vegetable Oil Esters)" (English) (Russian)

Posters

About GosNIIOkhT

For over 90 years GosNIIOKhT has worked in basic organic chemistry synthesis. Several of the largest Russian chemical centers were created based on GosNIIOKhT technologies, such as ones in Volgograd, Dzerzhinsk and Novocheboksarsk.

Areas of research

Currently GosNIIOKhT is one of the most prominent applied research organizations in organic synthesis. The Institute has a status of State Research Center and also is the leading R&D organizations in chemical demilitarization. The GosNIIOKhT is active in the following areas:

Development and putting in practice chemical demilitarization technologies, and operating the Chem Demil facilities;
Production of drugs (13 licenses for production of substances and dosage forms);
Toxicological study of drugs and industrial chemicals including preclinical testing and standards development;
Development of procedures for analysis of organic compounds for studies and production;
Drug discovery and development;
Chemical engineering and testing technologies at pilot scale;
Soil bioremediation;
Synthesis of new organic compounds.

Personnel

1000 employees;
144 PhDs;
31 Doctors of Science;
4 Scientific Boards;
Post-graduate school;
Diploma courses for students from leading colleges of the country;
Industrial training and a center for training of Chem Demil facility operators;

Facilities

2 Laboratory buildings;
2 Buildings for test facility;
Central Analytical Laboratory building;
Administration building;
Storage areas, workshops, transport ways, security;
Power and heat supply, ventilation systems;
Centralized communication system is being upgraded.

Organizational structure

Chemical Demilitarization Department;
Technology Development Department;
Synthesis Department;
Fundamental Research Department;
Central Analytical Laboratory;
Toxicology Department with vivarium;
Department of risk assessment and mathematical methods;
Laboratory of development of new drug forms;
Test facility for testing new technologies and equipment;
Facility for drug production in ampoules (GMP-standardized) and tablettes.

Interionational Cooperation

GosNIIOKhT has had partnerships with to cooperation with western companies such as:

Bechtel;
Battelle Memorial Institute;
Parsons;
Westinghouse;
PNNL;
Edgewood Research Center;
etc.

Three-phase development

First phase (1-2 years)
- Completion of development of QA/QC system and introduction of GLP and GMP standards at all stages of drug development and production;
- Acquisition of second ampoule production line to provide stability of production;
- Development of integrated center on drug discovery and development;
Second phase (2-4 years)
- Development of technologies and production of existing western drugs
- Involving GITOS affiliation into production of substances and dosage forms;
- Creation of bank of potential drugs and capability for drug scrinning;
- Getting not less than 25% share of the market of strong analgetics;
Third phase (6-10 years)
- Production of existing western drugs (not less than 30 drugs);
- Production of newly developed drugs (1-2 drugs);
- Getting a status of regional center on scrinning and preclinical testing of drugs;
- Getting not less than 60% share of the market of strong analgetics;
- Stable share on the market of general drugs.